Month: September 2010

The Cross and the Surgeons blade

Lakshmi is just 3 years of age, her father had vanished in thin air, may be the over consumption of alcohol was the reason, one day ‘blink’ he was not there.  Lakshmi has 3 sisters and her mother, Kuppayi, works as a tea picker on the hills.  Little Lakshmi was diagnosed with a heart ailment and she wanted urgent medical intervention.  So Kuppayi had to make frequent trips to the hospital for she knew not that her new born child was born with a cardiac ailment.

Kuppayi found favor in the eyes of the Chief Doctor who was a good man and spoke . kind words, at times he even told her stories from a thick black book.  Once he gave her a long piece of wood with another piece of wood across it and advised her to keep it under Lakshmi’s pillow. The only problem was Lakshmi did not have a pillow to sleep on so she had to rest the head on that piece of wood wrapped around a thin towel.  Lakshmi used to find this a bit painful in the night, and she pushed  it away.

The Doctor was a kind man indeed; the year was coming to an end.  As usual Lakshmi was in pains and Kuppayi ran to the hospital and the Chief Doctor was there, at peace with himself and relatively free.  Lakshmi got immediate attention, her crying had ceased and the Chief Doctor was narrating to Kuppayi about an incident that happened 2000 years ago. He said in a soft tone  “there was this little child, named Jesus, who was born in a lowly shed, the child’s mother and father were good people and they took care of the child.  Now when the child was 2 weeks suddenly the child was carried away to another country because the wicked king wanted to kill all children.  The king’s guards pierced a knife into the heart of every child and God helped baby Jesus escape. To Kuppayi, the story meant a lot, she lamented the fact that her husband was not there.  Was the wicked King trying to kill her own child, Lakshmi, by piercing a knife into her heart?  These thoughts were running in her mind.

Few days later, there was a ‘knife attack’ on the Lakshmi and Kuppayi ran to the hospital carrying her child.  Unfortunately the kind Doctor was not there, the ward boy said something about the doctor being on leave to celebrate a festival and that the Junior Doctor is in charge.

Kuppayi, waited near the door step of the junior doctor, who was not a kind man. He sported a rough face a harsh voice and seemed to be very rude with everybody. In short she saw the ‘wicked king’ in this Junior Doctor.  He was very niggardly with his smile and his constant smirk made Kuppayi very unhappy. After waiting for nearly 2 hours with her wailing daughter, she saw the junior doctor walk away.  Kuppayi ran behind him and she was shunned by the oversized nurse who walked along with the doctor.

The Doctor, without any change in expression, summoned Kuppayi and enquired of her in an unfriendly tone.  Kuppayi, with her limited knowledge, told all that she knew about the condition of the child.  The doctor, touched Lakshmi, actually poked her, and Lakshmi let out a scream.  Twitching his bushy eyebrows the doctor came up with the most insensitive   diagnosis “Your daughter will live only for 48 hours more if she does not get operated upon immediately”. And he even scolded Kuppayi for not seeking medical help for all these days. He refused to listen to her as she pleaded that she was a regular visitor to the Chief Doctor.

The next day the operation was fixed. Lakshmi was operated upon and within five days the nurse came and told Kuppayi that the child was fine and that she will be have to leave the hospital the next day.

Lakshmi was discharged and as Kuppayi was walking down the corridor carrying her child, she was delighted to see the Chief Doctor.  She narrated all the rough treatment she had received in the hands of the unkind doctor and about the operation too, and sobbed.  The doctor with a smile comforted the sobbing Kuppayi and said “Do you remember the story that when Jesus was born, the bad king tried to kill him” Don’t worry I am back, I will take care of you and handed over a nice piece of a brown cake with some toys, handful of balloons and a book with some colorful pictures.

Kuppayi’s happiness knew no bounds.  The kind doctor is back indeed. Her daughter need not be in the receiving end of the wicked junior doctor’s knife anymore nor does she have to listen to those harsh words.

The Chief Doctor went back to his cabin with this aura of satisfaction around him.  There was a heap of pending mails on his table.  Most of them were cards wishing him ‘Merry Christmas and Happy New Year’.  The Junior Doctor apparently forgot to wish his boss and it did not please the Chief Doctor. Instead  there was a file sent from him, and it was marked in red ‘FOR IMMEDIATE APPROVAL’ it was a letter requesting a special sanction for a free emergency surgery performed on Baby Lakshmi.  The Chief Doctor was livid; he pulled out his red pen like a sword and in anger, put a ‘cross’ on the note.  And wrote boldly across ‘NOT APPROVED, THE JUNIOR DOCTOR HAS TO PAY THE PRICE OF THE SURGERY FROM HIS SALARY’

Lesson on focus

Its important to think and ideate but to do it calls for a certain kind of ability that is very unique and distinct.  I found this  in an entrepreneur.  Over the past week I have had this privilege of interacting with some successful entrepreneurs.  Let me share one of my experiences with you.

Focus.

I will consider myself notorious for jumping from one topic to another.  Beyond a point in time my interest on one subject diminishes and its time for something new.  Now this action is primarily justified when related topics or those that are remotely connected are discussed.  For in the daisy chain of events, its important to consider a few related issues together in order to add value to the topic on hand.  Now this has a danger of moving away focus and dissipation of thought.  Over the past one week I realized the power of focus, sticking on to simplicity and basics.

I learnt this from my Entrepreneur friend who is painfully zealous in sticking to what is being discussed, often times shrugging off my foray into other issues.

Money and Net Joy

Haven’t you people say say its ‘tough to make the first million and then its a cakewalk’. And then there are people like who cares very little about money but his measure is providing jobs to millions. The scientists talk about a magic figure of 50k and then the net joy is the same beyond there weather its 100k or 10000k.

Net Joy? Food, at some point, can satiate a human, a drink can bring a man to a point of total tipsiness and after that it really does not matter if you are lining your intestines with scotch or plain water. If your job is to carry or tread on bundles of money will it become a object of repulsiveness?

Sometimes I wonder how it would like to be to be submerged in excess of wealth. Personally I would like to see others handling loads of money along with all the problems the accompany it, but I would like to have Whatever- I – Want -Whenever – I – Want. It does not matter if money can provide it for me.

There are times I have thought that money is a mere metric to measure success now that I have grown up I come to believe that the measure is sleep and regular bowel movements.

End of the day money grounds the dreamer to reality by being elusive to him/her. Wonder what eludes the one who has it in plenty. The little chicken wanted to cross the road, the chicken on the other side of the road asked this chicken “why would you want to cross?” for which the chicken replied “because there is better on the other side” For which the chicken on the other side replied “ahh!!! but were you are is the best.

I have never heard of chickens with silk stocking wanting to walk barefoot but every chicken wants to wear a silk stocking. So much for Net Joy

TiECON CHENNAI 2010
November 24
Chennai Convention Centre
TiECON%20chennai%202010_logo-all_RGB.jpg

Herding minds vs Merging minds

Collective decision making  or in info age terms  lets call it the crowdsourced decisions – does that make sense.  It sure conveys the point.  I heard people say that ‘two heads are better than one’.  In which case many heads should be  better than two.  It really does not work on that progression.  I remember this joke very vaguely.  One Indian = Ten Japanese and Ten Indians = One Jap.  That’s supposed to drive home this point that Indians cannot work together.

Tower of Babel by Lucas van Valckenborch in 1594

Image via Wikipedia

I recall the tower of Babel chaos.  Now a whole lot of people with Nimrod as the leader wanted to build this tower to reach out to heavens.  They set about their task.  God looks down from below and says “If as one people speaking the same language they have begun to do this, then nothing they plan to do will be impossible for them.” So God acknowledges that if people were to speak the same language nothing stops them from accomplishing whatever they want to achieve.

So God confused the tongues.

For many years I thought that was the reason for the multiplicity of languages in the world.  God wanted us to be away from each other.  I saw this amazing gadget called ‘pomegranate’ (phone) its apparently got some freakish features like coffee maker and what kind of caught my attention was ‘live voice translator’.  Can this gadget help us unify language again and lead us to Babel II.?

Now get two minds to work on one problem and be assured that the problem will have the best solution.  What happens is that the volunteers are able to combine weak neuronal activities residing in two separate brains to maximize performance.

What happens when two individuals are incompetent, it sure is not easy.  There is a cognitive fallacy in psychology, known as the Dunning-Krunger effect.  When incompetent individuals overestimating their skills to think that they are above average, its not logically possible though. If there is a person like that in the team he/she can severely damage performance.

When our subjective confidence is larger than the objective accuracy it leads to another fallacy known as the overconfidence effect.  So successful collaborations have problems to overcome, only then the tower can be built.

The pick of all this is the concept of ‘social loafing’  I have been witness to this.  When two minds are working fine and you add two more minds one runs the risk of reducing the social pressure of each individual in the group and will actually reduce the individual contribution.

Herding minds and getting minds together hence can make the difference between success and failure

Brain Plasticity explained

Take a lump of clay, flatten it and try sketching your name on it.  Its easy isn’t it?  Now take a metal and try sketching your name… ummmm you are struggling.  Now try sketching you name on a piece of plastic…. Its neither easy nor difficult.  A sharp object, possible a pin will help you do that.

Brain Plasticity is like that.  Brain is not clay that it can change easily nor is it metal that it cannot change. IT’S PLASTIC.  It can change.  How can you change it? By attentional focus and consistent behaviour.

So you can change your brain.  You may be rigid but your brain isn’t.  Well its all the same but.  I have heard many people who have keep saying “I cannot change”.  This should read is I DON’T WANT TO CHANGE.  Biologically they can.

How can this change happen?  If brain had been like clay, changes could happen very soon.  Since its plastic it takes time.  How long?

Typically three weeks?  In three weeks you can get your brain to accommodate a new task or open itself to something new.  Three weeks is not sacrosanct … I just said 3 weeks just to drive home the point that its neither easy not hard.

So Brain is not a machine at all.  It adapts very well to the changing world around us by modifying its structures and neural mechanisms. It rewires itself in response to the new demands place on its by the external environment.

Now how does this happen?

Now that you have fair idea on Brain Plasticity you can read what Kenneth Wesson says about Neuroplasticity- Experience and your Brain

A significant part of neural processing is the coding of sensory stimulation. Information enters the brain in the form of sensation, auditory  and visual information. All incoming stimuli, with the exception of data sent through the olfactory system, are first channeled through the thalamus—the “waiting room,” where sensory information is sent before going to the cerebral cortex where it is disaggregated into its constituent parts. Each element—color, motion, lines, angles or texture—is sent to a specialized region of the cerebral cortex for processing. The brain compares the new information to aspects of earlier experiences that are already stored in permanent memory. If a match is found, an appropriate response is performed. Our response time to familiar stimuli grows faster as those reactions become hard-wired.

Examining the brain at the macro level, the cerebral cortex is composed of four large lobes, each of which can be subdivided into as many as 200 functional areas. Damage to a particular cortical area can disrupt or destroy any given competency. With today’s brain-mapping techniques, we can predict precisely which capacities will be diminished or lost through damage due to disease, stroke, injury or disuse.
Without your brain’s high degree of variability, what would make you any different from the next person? There is a unique cytoarchitecture, representing the special cellular organization and the precise connections inside each human brain. Neural pathways connect the brain stem, cerebellum, and subcortical structures (including the limbic system) to specific areas of the cortex, which are rearranged by the minute to reflect our most recent experiences. Since nature only allows us one chance to make a fatal blunder, our neural circuits constantly update our version of the world, which we find full of opportunities to pursue and dangers to avoid. Developing efficient pathways is vital to our survival.
From a micro perspective, the brain is made up of neurons and glial cells. There are over 150 different kinds of neurons making them the most diverse cell type in the entire human body. The work of each neuron is to carry out the input-processing-output framework of our experiences. Twenty percent of our neurons are inhibitory in function.__ Their job is to suppress network activation to stop a particular response or behavior. (ADHD arises from an inability to stop a response to one stimulus and choose to respond in a more appropriate manner instead. While this is often referred to as an attention deficit, it is more accurately an executive function deficit.)

Glial cells serve as “nannies” to the neurons. They transport nutrients and oxygen to them and remove debris from them, keeping neurons healthy and alive. Each human brain has over 100 billion neurons: the brain’s “gray matter,” which is composed of neuron cell bodies. Glial cells, however, far outnumber neurons; there are 10 to 50 times more “nannies” than neurons in the human brain.
Neuroscientists are fond of saying, “Neurons that fire together, wire together” and “Neurons not in sync, do not link.” Dendrites form tree-like extensions that put a neuron in touch with as many as 200,000 of its neighbors, resulting in what we call new thinking and learning. When the brain learns, new dendrites grow. Early brain theorists believed that with each new memory, a new neuron grew. Today, we know that newly learned information is encoded as new dendrites sprout to connect neurons to specific sites, producing a new pathway that represents the experience.
In order for us to move, feel and think, neurons relay messages to one another, using both electricity and chemistry. Once incoming stimuli reach a threshold point, a 270 mph electrical impulse “fires” down the axon. Once the electrical impulse reaches the end of the axon, a tiny pocket of chemicals bursts, sending neurotransmitters (the “chemical couriers”) across the synapse, the microscopic space between neurons. As neurotransmitters cross the synaptic gap they lock into receptor sites on the postsynaptic neuron and convey their chemical message only if their molecular properties fit the precise configuration of the receptor sites on the postsynaptic neuron. Over one quadrillion (1,000 trillion, or 1015) synaptic connections can be established inside the human brain.
__ To optimize message transmission, myelin, a fatty substance, coats the long axonal region of a neuron, speeding up signaling and insulating the axon from extraneous electrical or chemical impulses. A breakdown in myelin exposes the axon to misdirected electrical impulses. When diverted to unintended neurons, extraneous impulses can have devastating mental and physical consequences. Multiple sclerosis is caused by progressive degeneration of myelin.
__ Different regions of the brain become heavily myelinated during pre-programmed sensitive periods, which opens up windows of opportunity for developing specific skills or competencies. After a region is myelinated, a performance permanence sets in. Language-learning is one example. Every brain begins life with the capacity to learn any of the 6,000 languages spoken on Earth. When a child consistently hears the regular sounds (phonemes) in a given language, neural connections are created in the auditory cortex. The “window” for language-learning closes with the onset of puberty. Afterward, learning a new language will be more difficult and will typically be accompanied by a noticable accent.

Pruning the garden of the brain

Synaptic proliferation is the prenatal overproduction of synapses that gives a young brain its incredible adaptability. We are born with many more connections than our adult brains will use. This neural insurance policy guarantees that infants born in San Francisco, Shanghai or Soweto can flourish with equal ease. In the first two decades of life, the human brain “prunes” away connections in a dynamic self-reorganization that operates by the use-it-or-lose-it principle.

There is an old story about a man who walked from his farmhouse to his barn every day. After following the same path day in and day out, it wore into a groove. Eventually, the old man could walk to the barn blindfolded, since the deep channel would steer him directly where he was going. Neural pathways in the brain follow a similar pattern: They are strengthened with repeated use, while neglected networks become unreliable and eventually are pruned away.
Pruning helps the brain protect itself from devoting precious resources to useless networks and inefficient over-wiring. Apoptosis, programmed cell death, eliminates unneeded neurons, just as roads that are seldom traveled fall into disrepair and eventually are closed down for good. Unused skills suffer a similar fate: what we call “forgetting.” (While memory failures are generally due to degraded neural networks, accelerated memory loss is associated with stress, aging or acute brain damage.) Decreased use of skills reduces the nourishment of their networks, diminishing memory and performance.
In the absence of nearby land, some tadpoles will arrest the natural process of metamorphosis into frogs, because environmental conditions suggest that such a change is by no means beneficial to survival. Instead, those tadpoles remain swimmers. It is an apt metaphor for the developing brain.
Mother Nature offers a trade-off: instinct or flexibility. Those species whose behavior is dominated by instinct—e.g. reptiles, fish, amphibians, and insects—have brains that leave little room for neuroplasticity but are highly efficient. As a result, they are less adaptable. Human brains, on the other hand, were shaped by evolutionary pressures that rewarded adaptability. One example of our flexibility is the way our brains accommodate stimuli in multiple patterns and formats, but still accept them as the same object [see Chart 3: The Letter A].

Early Brain Growth

Neurogenesis is the rapid production of brain cells in utero, when neurons are produced at the incredible rate of 250,000 to one million per minute. The rapid growth of the young brain system begins 18 days after fertilization. The brain develops quickly through first-hand experiences. Computer simulations and early-learning videos are no substitute for the real world. A mere picture of an orange short-changes the learner, who cannot directly experience its smell, texture, taste and mass. Learners create meaning from what they do in their world, not from exposure to its representations.
While genetics and prenatal influences may calibrate the brain at birth, it is largely dependent on subsequent experiences to determine its capacities and deficiencies. Author Joseph Epstein stated, “We are what we read.” Neuroscientists would assert, “We are what we experience.” Neural circuits are constantly reorganized and rerouted, based on the quantity, quality and timing of our experiences. This has profound implications for what we should do in every home and school.
The stimulation young children receive from early interactions determines how their brains develop in the crucial postnatal period, when experiences have a decisive impact on the brain’s architecture and later capabilities. Brain cells create connections each time we integrate something new. Whether we are learning to crawl or dance, these experiences create brain pathways that capture what we know and who we are.
In its early years, the brain goes on a connectivity binge. The immature brain quickly links hundreds of millions of neurons together, forming efficient brain circuits [see Chart 4: Neural Connections]. During these stages, children make learning look easy. By adding, removing, or changing the strength of the connections among neurons, linking cells together or eliminating brain cells from existing neural pathways, neuronal activations change, making specific new learning possible. The word specific must be underscored here. All learning must be specific and transferable if it is to have any currency.
Creating new neural pathways is physically exhausting. The infant brain requires near-constant feeding to keep up with the energy consumption necessary for early brain development. Infants tax their energies when they are learning how to walk, talk, think, speak and remember, along with familiarizing themselves with all of the people, places and objects in their environment. Toddlers must also learn the complexities of language, and must master critical cultural and socialization skills. All of these are the minimum challenges that must be successfully and simultaneously met for adaptation to the environment. Synaptic connectivity maxes out during the second year of life. At its peak level, each neuron averages 15,000 connections. That number occurs in the early years of child development, when a toddler’s brain consumes 225% of the energy of an adult brain.
__ Enrichment studies have shown that a caring environment aids learning and development. But neuroplasticity also has a darker side. Impoverished environmental conditions, prenatal substance exposure, sensory deprivation, emotional trauma and nutritional deficiencies can cause plasticity to play its unkind hand, wreaking havoc on the developing young brain. Long-term chronic stress (“toxic stress”) provokes the release of high levels of the hormone cortisol that can lead to permanent damage to hippocampal neurons, causing learning difficulties and memory impairments.
__ On the brighter side, the human brain responds favorably to emotional support, challenge and steady constructive—it need not always be positive—feedback by increasing the myelination and nourishment of neural pathways. Individuals who are blind at birth have highly resilient brains eager to compensate for any deficiency. With their acute hearing ability, some of the world’s best musicians have emerged among the blind. In the absence of appropriate stimulation, the brain reassigns underutilized areas for other, sometimes completely different, functions.

Learning

Failure is not an option is a popular educational mantra that was unwisely borrowed from the business world. It inaccurately reflects how the young human brain learns. Students who struggle in school often appear to be impervious to the best efforts of well-trained professionals. The notion of “rigor” becomes almost academic rigor mortis for them. In nearly all cases, each learning difficulty is indicative of a neurological underinvestment in the necessary brain wiring needed to be successful. When we point to a concept or skill that is not “developmentally appropriate,” the reference we are making is to brain development, not curriculum development.
__ With this backdrop, certain academic shortcomings are expected. However, these events foster frustrations when the child “doesn’t get it.” With time, maturation and the appropriate brain wiring, s/he will one day “get it.” When it comes to learning, failure is often a prerequisite. This is particularly true when learners lack related prior experiences, as the new information cannot merge with brain circuits that don’t exist yet. When there is nothing with which to integrate new knowledge, the building process must begin from scratch. The child is not “slow”; the process of brain-building is sometimes slow.

Expertise

In Outliers: The Story of Success, author Malcolm Gladwell hypothesizes that exceptional performances in any field have little to do with innate talent. He proposes the “10,000-Hour Rule”: devoting approximately 10,000 hours of time to a skill fosters a dendritic density representing competency in that area. Whether we are examining achievement in academics, professional careers, athletics or public speaking, practice makes permanent, not perfect, when it comes to the human brain.
__ Long years of continuous practice create the hard-wired neural pathways of proficiency and expertise. Complex interconnections among the pathways in the brain give an expert four distinct neurological advantages:
1. Highly used neural pathways are easily activated, because they are nearly always “on alert.”
2. Extensive hardwiring provides neural “shortcuts” to answers that their under-wired counterparts might find puzzling for hours, days, years or forever.
3. Their jam-packed cognitive tool chest serves as a repository of information, precluding the time-consuming data searches required by others.
4. Most importantly, cognitive resources are freed up to engage in ideational exploration and conceptual processing. The question asked about experts such as golfer Tiger Woods changes from “Is he any good?” to “Is he always that good?”

Experts routinely take the time to learn, unlearn and relearn relevant information related to their craft. For them, learning is not an informing experience, where they simply build networks to represent their new experiences; instead, their experience is transforming: Their brain circuits are rearranged in order to integrate new data.

The Future of the Brain

With each major advance in the human condition over the past 4.5 million years, our brain volume has increased to accommodate our behavioral improvisations. Is the human brain on the doorstep of another “brain spurt”? [See Chart 5: Brain Spurts]. Our evolutionary history would suggest that we may be. The remarkable world of technology will likely be accommodated by an even more remarkable brain plasticity.
__ As we come to the close of the first decade in the 21st Century, we recognize that we are living in a unique, historic time. Neuroplasticity is shaping today’s young brains for a future that is less like our recent past than any other time in human history. Technology is extending the range of human information processing, shattering the previous limitations of our sensory systems. Previously, the walls of time and place dictated the scope of the human experience. These barriers are falling rapidly.
__ If you are a parent, educator, or anyone charged with the responsibility of developing young minds, brain literacy is no longer optional. When you are asked by your former students, children or grandchildren, What did you do to help me when that new research on the brain suddenly became accessible to you?, hopefully, your answer will be, I did everything I could, based on everything we knew from every field in neuroscience at that time.

Lessons from blowing bubbles

These late night chats can throw up deep thoughts at times.  So it was as I chatted with my friend very casually.  Learning the lessons in life and taking charge of it is mans desire, and this is thwarted by the most expected events that are likely to throw the entire thing off balance.  Yet one is witness to many who seem to have mastered the art.  Come close you realise that they have shaped themselves to be a machine.  Then you wonder is this charge that you desire in life worth it?

I would rather live one day having total control of my life and die thereafter.  Does that make sense?  surely not.  Why would you want to have control over your life anyway?  when the improbables and the unexpected are there to throw those occassional surprises like how salt is mixed on to a dish.  Why would one say no to the spices of life?

Mind wanders to the days when at the fun fair, as children, we were facinated by the man who always stood near the gate selling a crude contraption that made soap bubbles.  It was facinating for use.  The bubbles floated all around, they reflected the colors of the rainbow, some were small and some big.  Some burst in mid air and some resided secure but burst.  There were many lessons from the soap bubbles about life, and in fact there were many lessons that could have been derived from the mundane things in life.  These lessons are often learnt after the mistakes are made.  Because the goofups are the ones that open you eyes towards the lessons life can teach.

In conclusion one actually decided not to envy the ones who take charge of their lives, for they have decided to live it bland and tasteless.